Reborn takes place several years after the events of the second book, Near Death. The half human, half vampire child, Michel is now grown and on the verge of immortality. The story begins with the shocking murder of an ancient vampire, which throws this close knit group of the undead into a tailspin. They have a sense of who is responsible and with the help of the vampire Karl and his scientific methods end up sure of the murderer's identity. This monster is old and powerful and the community is torn between wanting to attack or retreat.

In the midst of chaos, Karl's partner Gerlinde is missing. He leaves the others behind and goes off along in search of her, despite warnings from his friends that the murderer will find him easy prey. But he cannot exist without his lover and eventually is confronted with an existential question that rips him apart: should he exist at all?