Dr. Gert Bower's day goes bad fast when she accidentally releases an abominable monster of the abyss on the streets of New York City. Desperate to stop it, she turns to the only person who can help her track the monster down. Vi De Luca is a private detective and creature of the night, a vampire more than willing to help Gert—for a price.

In exchange for catching the monster, Gert must spend one night with Vi, and let Vi have her way with Gert's blood and body. Though she does not remotely trust Vi, for the good of the city Gert agrees. Yet tracking the monster turns out to be more than either of them had bargained for. When Gert embarks on an experiment to try and reanimate a human corpse things just keep getting worse.