Oprah Winfrey: Only the biggest stars are known by just their first name. Oprah is one of them. As host of The Oprah Winfrey Show, she reaches millions of people every day. Yet Oprah is much more than a talk show host. She is the queen of a growing media empire, runs charities, and recently opened a school for girls in South Africa. Her hard work has brought her incredible wealth and power. She uses both to spread her influence and help other people.