Consulting detective Sherlock Holmes and his colleague Doctor John Watson return in Sir Arthur Conan Doyle's second collection of Holmes stories—The Memoirs of Sherlock Holmes. This volume includes the stories "The Adventure of the Cardboard Box," "The Adventure of the Musgrave Ritual," and "The Final Problem," in which Holmes first confronts his most deadly adversary: the brilliant criminal mastermind Professor James Moriarty.

Doyle's Sherlock Holmes stories have been adapted numerous times, including the 2009 and 2011 movies starring Jude Law and Robert Downey Jr., and for the popular television shows Elementary, starring Jonny Lee Miller and Lucy Liu, and the BBC's Sherlock, starring Benedict Cumberbatch and Martin Freeman.

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