The Queen of bullies, Jessica, received her just punishment. Her soul was taken from her body and placed inside one of the Voodoo dolls adorning the tombstone of the girl she had tormented most. But Jessica is far too smart to remain there forever.
She tricks a sixteen-year-old girl into picking up her doll. Taking over the girl's body comes with an unintended side-effect—the real girl's soul is cast out and disappears. Jessica doesn't have time to mourn. She needs to free the other trapped souls inside the other dolls around the grave.
The last trapped soul is Jessica's best friend, Claire. She can't bear the thought of Jessica killing the girl to escape the body so she asks to take it over, instead. With Claire now inside the body of the sixteen-year-old girl, Jessica's spirit is finally free. Yet, she can't seem to leave like the others did.
With nowhere else to go, Jessica's ghostly form tags along with Claire in her new body. They find themselves having to repeat the high school experience, except this time, Claire's new body is anything but popular. Tortured and demined by nearly every kid at school, Claire and Jessica gain a whole new perspective on what was wrong with how they acted to others back in high school.
They find out that Claire's real body is on life support in the hospital, but neither Claire nor the ghostly Jessica is able to take over the body. Then the spirit of Jessica disappears for hours until flickering just enough for Claire to be able to follow. She discovers Jessica's real body in a secret basement of the woman who trapped them inside the dolls in the first place.
Once they discover they must return to their bodies before the next full moon or forever remain in their mixed up state, time does not seem to be on their side—but a whole herd of nerds are. With their help, Jessica and Claire retrieve their rightful bodies and perform a ceremony that puts all souls back where they should be, including the sixteen-year-old girl.