Cherry, Nebraska, population 312, is just off the highway between the sticks and the boonies. It's where Dave Rhodes and his friends have lived all their lives. They own businesses, raise families, pay taxes, deal with odd neighbors, and, once or twice a month—just like their fathers before them—transform into wolves.

It's not a bad life, but when one of the group members goes astray, it sets in motion a series of events that will threaten to destroy the delicate balance that has kept Dave and his clan off the radar. Between a son getting ready for his first transformation—called The Scratch—a wife with sordid secrets, a new sheriff who knows nothing of the creatures in his midst, and a mysterious man in a bow tie with a shady agenda, the middle of nowhere is about to get very dangerous.