The question of man's place in the extended universe has been pondered by every known culture since the beginning of recorded history. Lacking the means to prove otherwise, discussions of an alternative to Earth's solitary existence have remained conceptual. The ongoing debate is spurred by the appearance of unexplainable phenomena through the centuries in the atmosphere and the space beyond. Naturally, as technological advances and the creation of flying aircraft became realities, the sighting of UFOs increased, as did the interest in potential contact with aliens. While incidents like the one at Roswell led to conspiracies and a craze among those who insisted the government was hiding proof of extraterrestrials' existence, governments across the world were actually secretly studying UFO sightings by the mid-20th century.

Given all of that, it would hardly be groundbreaking for scientists in the 20th century to have a lunchtime discussion in which the search for extraterrestrial life arises, and the question of where it might reside is innocuous enough. However, a furor was created somewhat innocently when physicist Enrico Fermi voiced his "casual lunchtime remark" in the presence of colleagues in 1950. The august company included Edward Teller, a Hungarian physicist, Herbert York, am American nuclear physicist whose lineage included Mohawk heritage, and Emil Konopinski, a nuclear physicist of Polish origin. Fermi himself, an Italian-American born in Rome, was renowned for developing a statistical base for subatomic phenomena, work on nuclear alterations caused by neutrons, and for leading the first controlled chain reaction from nuclear fission. In pursuit of managing the atom, he created the first nuclear reactor. A gifted theoretician, he advanced the field of statistical mechanics, and won the Nobel Prize over a decade before he asked his important question.