He told her to run. And she did. As fast as her legs would take her, but it wasn't fast enough...

The bodies of a husband and wife are found in a patch of woods in small-town, rural Arkansas by a neighboring farmer. They were shot with an arrow, gutted, and left to bleed out. The killer also removed their eyes and replaced them with large cat's-eye marbles. The murder method and signature are too bizarre to point toward an isolated incident, and FBI Special Agent Brandon Fisher recognizes this right away. His boss with the Behavioral Analysis Unit, Supervisory Special Agent Jack Harper, confirms that he's crossed paths with this killer several years ago, and he has a voracious appetite for blood. In fact, Jack's seen his work firsthand—six times, three couples, in three states.

Brandon, Jack, and the rest of the team head to Arkansas for one purpose: to bring down the ruthless and elusive serial killer who calls himself "the Leopard." Versatile and adaptive, this madman hunts his prey like a wild, hungry cat—tracking them, then striking with swift viciousness. But just as the FBI think they might finally be getting closer to the Leopard's true identity, he adapts his method and starts killing people faster than ever before.

Racing to catch up, and struggling to get one step ahead, the FBI comes to uncover buried family secrets that aid the investigation—while at the same time, flipping it on its head. Suddenly, the hunters are now the hunted. And while this case has haunted Jack since he joined the Bureau, things are about get more personal and dangerous than he ever would have imagined. If he and his team aren't careful, one of them—or someone they love—may become the Leopard's next victim.