Research scientist Dr. Marina Singh is sent to Brazil to track down Dr. Annick Swenson, who has disappeared in the Amazon while working on a valuable new drug. The last person who was sent to find her, Marina's research partner Anders Eckman, died before he could complete his mission. Plagued by trepidation, Marina embarks on an odyssey into the insect-infested jungle in hopes of finding her former mentor as well as answers to several troubling questions about her friend's death.