Collects Amazing Spider-Man (2015) #16-19 and material from Free Comic Book Day 2016 (Captain America) #1. Going global means a world of problems for the wall-crawler! First, there's an accident to deal with at Parker Industries. How far will Peter Parker go to save his employees — both as CEO and as Spider-Man? Meanwhile, stand-in Spidey — the Prowler — meets the shocking, all-new Electro! Then, the moment you've been waiting for: Doctor Octopus has been trapped in the Living Brain's body for too long — now it's time for him to act! And when someone in Peter's orbit dies, he must once again choose between his personal life and the responsibility of being Spider-Man — and that choice won't go well for him! Plus: both sides of a special tale setting the scene for the sensational Spider-Event "Dead No More"!